Free Resources
Research & Guidelines
Explore selected clinical guidelines, recommendations, landmark studies, and published research addressing testosterone deficiency, testosterone therapy, prostate health, cardiovascular health, and related areas.
01 — 5 publications
Clinical Guidelines & Recommendations
Professional guidelines, consensus statements, clinical recommendations, and position statements related to testosterone deficiency and therapy.
- Guidelines & RecommendationsDiagnosis and Treatment of Testosterone Deficiency: Updated RecommendationsView Article→
- Guidelines & RecommendationsEvaluation and Management of Testosterone Deficiency: AUA GuidelineView Article→
- Guidelines & RecommendationsA Critique of the AUA Guidelines on Testosterone DeficiencyView Article→
- Guidelines & RecommendationsISSWSH Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in WomenView Article→
- Guidelines & RecommendationsRecommendations on the diagnosis, treatment and monitoring of hypogonadism in menView Article→
02 — 8 publications
Prostate Cancer & Testosterone
Research examining testosterone therapy, prostate cancer, prostate health, and the evolving evidence surrounding their relationship.
- Prostate Cancer & TestosteroneTestosterone Does Not Drive Prostate Cancer: Presenting the New Framework of Androgen Adequacy vs InadequacyAbraham Morgentaler, MD, FACS and Abdulmaged M. Traish, PhD · The Journal of Urology · 2026A review of the evidence examining the relationship between testosterone and prostate cancer, together with a new framework of androgen adequacy versus inadequacy for understanding prostate pathophysiology.Published Research · Special ArticleTestosterone Therapy · Prostate Cancer · Safety · Androgen Adequacy · Saturation ModelView Published Article→
- Prostate Cancer & TestosteroneStrategies for Testosterone Therapy in Men with Metastatic Prostate Cancer: Introducing Modified Bipolar Androgen TherapyView Article→
- Prostate Cancer & TestosteroneTestosterone Therapy in Men with Biochemical Recurrence and Metastatic Prostate Cancer: Initial ObservationsView Article→
- Prostate Cancer & TestosteronePrevalence of prostate cancer among hypogonadal men with prostate-specific antigen levels of 4.0 ng/mL or lessView Article→
- Prostate Cancer & TestosteroneTestosterone Therapy in Men With Prostate Cancer: Scientific and Ethical ConsiderationsView Article→
- Prostate Cancer & TestosteroneTwo Years of Testosterone Therapy Associated with Decline in Prostate-Specific Antigen in a Man with Untreated Prostate CancerView Article→
- Prostate Cancer & TestosteroneA New Era of Testosterone and Prostate Cancer: From Physiology to Clinical ImplicationsView Article→
- Prostate Cancer & TestosteroneOccult Prostate Cancer in Men With Low Serum Testosterone LevelsView Article→
03 — 3 publications
Cardiovascular Health
Research addressing testosterone deficiency, testosterone therapy, cardiovascular disease, cardiovascular risk, and related outcomes.
04 — 5 publications
Testosterone Deficiency & Treatment
Research related to the diagnosis, physiology, clinical consequences, and treatment of testosterone deficiency.
- Testosterone Deficiency & TreatmentTestosterone DeficiencyView Article→
- Testosterone Deficiency & TreatmentFundamental Concepts Regarding Testosterone Deficiency and TreatmentView Article→
- Testosterone Deficiency & TreatmentRecognizing the True Value of Testosterone Therapy in Health CareView Article→
- Testosterone Deficiency & TreatmentA Multi-Institutional Observational Study of Testosterone Levels after Testosterone Pellet (Testopel®) InsertionView Article→
- Testosterone Deficiency & TreatmentBone Mineral Density and Response to Treatment in Men Younger Than 50 Years with Testosterone Deficiency and Sexual Dysfunction or InfertilityView Article→
05 — 5 publications
History, Evidence & Evolving Concepts
Publications addressing the historical assumptions, controversies, and changing scientific understanding of testosterone therapy.
- Evolving EvidenceThe History of Testosterone and the Evolution of its Therapeutic PotentialView Article→
- Evolving EvidenceTestosterone and Prostate Cancer: An Historical Perspective on a Modern MythView Article→
- Evolving EvidenceRisk of Testosterone Flare in the Era of the Saturation Model: One More Historical MythView Article→
- Evolving EvidenceGuilt by Association: A Historical Perspective on Huggins, Testosterone Therapy, and Prostate CancerView Article→
- Evolving EvidenceGoodbye Androgen Hypothesis, Hello Saturation ModelView Article→
Links open the publication on the publisher’s website or as a PDF in a new tab. All T4L Education resources are provided for educational purposes and are not intended as a substitute for professional medical advice.